Much about the devastating neuromuscular disease amyotrophic lateral sclerosis, or ALS — and also known as Lou Gehrig’s Disease — remains a mystery. But researchers have been learning more about the factors the underlie the complexities of the disorder — some new knowledge pointing to a range of environmental agents as possible risks factors. Research by Fulton Schools Professor Rolf Halden and two doctoral students in Halden’s Biodesign Center for Environmental Health Engineering is focused on exploring environmental influences potentially linked to the disease. Using rigorous quantitative methods, they are examining the complicated interplay of various environmental and physical dynamics in the hope of revealing a distinct pattern of causality related to the disease.