ASU scientists boost gene-editing tools to new heights in human stem cells
The promise of improving human health with use of the gene-editing tool called CRISPR has been limited because its editing capabilities are often imprecise. But David Brafman, a Fulton Schools assistant professor of biomedical engineering, is at work on developing ways to improve CRISPR’s efficiency. Results of his efforts published in the research journal Stem Cell Reports details how Brafman’s lab team has developed a new approach to enriching DNA base-edited cell populations. The genetic modification of stem cells enabled by this method looks as if it will be useful for disease modeling, drug screening and tissue engineering, and for revealing the causes of Alzheimer’s and other neurodegenerative diseases. The article has also been published on Phys.Org, Science Codex and Technology Networks.
See Also: Gene-editing taken to advanced levels in human stem cells, News-Medical.net, January 20